Focusing on the methodological challenges in adapting tissue optical clearing technology to large animals, this review systematically examines the key bottlenecks in transitioning from rodents to large animals, summarizes representative applications in neural circuit mapping and sensory organ visualization in large animal, and offers perspectives on future research directions.

The appearance of a hot sauce or pepper doesn’t reveal whether it’s mild or likely to scorch someone’s taste buds. So, researchers made an artificial tongue to quickly detect spiciness. Inspired by milk’s casein proteins, which bind to capsaicin and relieve the burn of spicy foods, the researchers incorporated milk powder into a gel sensor. The prototype, reported in ACS Sensors, detected capsaicin and pungent-flavored compounds (like those behind garlic’s zing) in various foods.

A team of researchers from Tianjin University has developed a novel tree-like nitrogen-doped carbon (T-NC) support structure that addresses key challenges in fuel cell technology—cost, performance, and durability. Published in Front. Energy, this innovation enables low-platinum (Pt) loaded fuel cells to deliver superior efficiency and longer lifespan, bringing the widespread commercialization of hydrogen-powered vehicles one step closer.

Researchers at Beijing University of Technology have developed a new type of acid-stable bimetallic phosphide-silver core-shell nanowire catalyst that significantly improves the efficiency of the hydrogen evolution reaction (HER)，which was published in Frontiers in Energy

An international team of scientists from three continents led by Dr. Petr Cígler of IOCB Prague has developed a method for creating light-emitting quantum centers in nanodiamonds in only a matter of minutes. In just one week, the process can yield as much material as conventional methods would produce in more than forty years. Moreover, the resulting nanodiamonds show improved optical and quantum properties. The breakthrough brings us one step closer to the industrial production of higher-quality and more affordable quantum nanodiamonds, which have broad applications in research and technology. The article was published in the scientific journal Advanced Functional Materials.