New metric predicts the likelihood of amyloid presence and leads the way in early Alzheimer’s detection
Peer-Reviewed Publication
Updates every hour. Last Updated: 3-Nov-2025 14:11 ET (3-Nov-2025 19:11 GMT/UTC)
ROCHESTER, N.Y. (May 14, 2025)—Neuroscience technology innovator Cognivue®, today announced a scientific breakthrough with the launch of the Cognivue Amyloid Risk Measure (CARM)*, a novel metric that predicts the likelihood of the presence of amyloid—a key biomarker of Alzheimer’s disease (AD).1 Now available as an optional feature on the Cognivue Clarity® device (based on FDA-cleared technology), CARM represents a significant advancement in the early detection of Alzheimer’s by helping healthcare providers identify those at risk of cognitive impairment, even before symptoms emerge.
Over time, stress and anxiety can build to a point where life’s challenges become overwhelming and cause physical effects. Now, in ACS Applied Materials & Interfaces, researchers report a dental floss pick with a built-in sensor that could monitor stress as part of a daily routine. The device, which accurately senses levels of the stress hormone cortisol in minutes, could help users recognize when it’s time to get help.
In many neurodegenerative diseases, proteins misfold and clump together in brain tissue. Scientists developed a new therapy made of peptides and a sugar that naturally occurs in plants. The therapeutic molecules self-assemble into nanofibers, which bond to the neuron-killing proteins. Now trapped, the toxic proteins can no longer enter neurons and instead harmlessly degrade.
When biting into a chili pepper, you expect a fiery sensation on your tongue. This spiciness is detected because of capsaicinoid compounds. But for some peppers, despite high levels of capsaicinoids, the heat is mysteriously dull. Now, researchers reporting in ACS’ Journal of Agricultural and Food Chemistry have identified three compounds that lessen peppers’ pungency. These results challenge the reliability of the century-old Scoville scale, which traditionally bases its rating on two capsaicinoids.
A new study published in the journal Environmental Science & Technology examined associations between diet, drinking water, and “legacy” PFAS—chemicals that were phased out of production in the US in the 2000s—with blood samples from California residents. PFAS exposure was associated with consumption of seafood, eggs, and brown rice, but fewer other foods than suggested by earlier studies. PFAS levels were elevated among people who lived in areas where these chemicals were detectable in their drinking water supply, but lower than levels found in highly contaminated communities.
Researchers at the University of the Basque Country (EHU) have explored how a combination of photovoltaic energy and heat pumps could be used to carry out the energy retrofitting of social rental housing. The Basque Government’s Zero Plan was used as the basis, and the technologies that the European Union is keen to promote were assessed. The buildings in Araba-Álava were generally found to offer the greatest potential for implementing the system.