A research paper by scientists at Beijing Institute of Technology presented a CFD simulation method based on biological experimental data to analyze the aerodynamic performance of pigeons during takeoff, leveling flight, and landing in free flight.

Novel cancer therapy combining multi-hydroxylated fullerene (MF) nanoparticles and mTOR inhibitors triggers organelle cascade collapse in tumors, disrupting cancer cells' self-repair capacity. By synchronizing the membrane-breaking effect of MF with dual autophagy regulation, this strategy induces lysosomal rupture, mitochondrial dysfunction, and endoplasmic reticulum stress while paralyzing cellular cleanup systems. Animal studies demonstrate potent tumor suppression and high safety, leveraging cancer cells' fragile organelle networks against them. The breakthrough establishes organelle communication disruption as a new anticancer paradigm, pioneering material science-enabled therapies independent of genetic targets.

Mononuclear macrophages serve as the primary target cells for the in vivo metabolism of iron-based nanomaterials. The uptake of nanoparticles by mononuclear macrophages is influenced by various factors, such as particle size, surface charge, and administration route, which subsequently affect the metabolic process. During this process, iron-based magnetic nanomaterials can induce macrophage reprogramming and participate in immune modulation. This is primarily reflected in their regulation of macrophage function through enzyme-like activities, intracellular iron metabolism, cell signaling pathways, mitochondrial energy metabolism, and responses to magnetic fields.