Controlling the state of a cell in a desired direction is one of the central challenges in life sciences, including drug development, cancer treatment, and regenerative medicine. However, identifying the right drug or genetic target for that purpose is extremely difficult. To address this, researchers at KAIST have mathematically modeled the interaction between cells and drugs in a modular “Lego block” manner—breaking them down and recombining them—to develop a new AI technology that can predict not only new cell–drug reactions never before tested but also the effects of arbitrary genetic perturbations.

Imagine using one laser beam to 'write' instructions into a material and another to 'bend' it into a complex, functional shape—all on the spot, without moving a thing. Researchers at the University of Science and Technology of China (USTC) have turned this concept into reality, developing a novel dual-laser method that creates adaptive, shape-locking devices in situ.

In the International Journal of Extreme Manufacturing, A novel conductive hydrogel, termed AirCell Hydrogel and developed by Tianjin University researchers, exhibits an ultra-high sensitivity of 18.9. Its smooth surface enables conformal adhesion that effectively suppresses motion artifacts, while its porous interior structure lowers the Young's modulus during deformation tracking.

POSTECH-UCLA Collaborative Team Develops Novel ‘Univody’ Platform for Antigen-Independent Cancer Immunotherapy.

A new review in International Journal of Extreme Manufacturing highlights the rapid progress in turning metallic materials into flexible electrodes (FEs) and, ultimately, soft epidermal electrodes (SEEs). Unlike the rigid metal pads traditionally used in medical monitoring, SEEs are engineered to mimic the softness and stretchability of skin itself. They conform like a second layer of tissue, remaining comfortable even during long wear and delivering stable, high-quality signals.

The researchers are investigating the interaction of different cell types at the border between blood vessels and the brain. A particular focus here is on sex-specific differences.

In International Journal of Extreme Manufacturing, researchers used a carefully tuned femtosecond laser under water immersion to etch nanogratings just 46 nanometers apart with groove widths near 13 nanometers onto highly oriented pyrolytic graphite (HOPG). It addresses a long-standing challenge: fabricating uniform structures smaller than 100 nanometers.