Researchers have developed the first platform of its kind that allows dynamic visualization of male reproductive function in living mice. In findings published in MedComm, they describe an approach that enables non-invasive, real-time monitoring of male fertility over time.

Despite its importance to the survival of our cells, the processes of plasma membrane repair have remained elusive. Their relevance is underscored by the fact that mutations in plasma membrane repair proteins cause various diseases, likely arising from cell death due to unrepaired plasma membrane.

But now, researchers at the Okinawa Institute of Science and Technology (OIST) have captured this repair mechanism in new detail. Using budding yeast as a model organism, they identified 80 proteins involved in plasma membrane repair, 72 of them never reported before, and tracked their movements in real time. 

A research team at Chalmers University of Technology, Sweden, has developed new laser technology that could lead to tiny, cost-effective biosensors. The sensors integrate lasers and optics together on a centimeter-sized chip, which could move testing from hospitals to patients' homes. This, in turn, would free up hospital beds and reduce visits to clinics.

Psychiatric diagnosis still relies on symptom checklists that were never designed to reflect biology. A peer-reviewed invited review published in Brain Medicine now synthesizes recent advances across four converging domains: conceptual frameworks that move beyond categorical labels, molecular and neurobiological biomarkers, digital phenotyping through smartphones and wearable devices, and machine learning approaches capable of integrating these heterogeneous data streams. The review authors, based at the University of Cambridge, argue that combining objective biological measurement with clinical judgment could yield diagnostic subtypes that predict illness trajectory and guide personalized treatment. They also identify formidable barriers, from data scarcity and algorithmic opacity to regulatory fragmentation and the risk of deepening health inequities.

A research team led by Dr. Sung Mook Choi of the Energy & Environment Materials Research Division at the Korea Institute of Materials Science (KIMS), in collaboration with a team headed by Professor Seung-Hwa Lee at Changwon National University, has successfully designed and developed a proprietary non-precious metal oxygen evolution reaction (OER) catalyst featuring a layered structure optimized for anion exchange membrane water electrolysis (AEMWE) environments.

In their Research review article, “Generative Artificial Intelligence in Medical Imaging: Foundations, Progress, and Clinical Translation,” Hairong Zheng and Shanshan Wang (Paul C. Lauterbur Research Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.) et al. provide a comprehensive overview of recent advances in generative modeling for medical imaging.

POSTECH Professor Jonghun Kam’s team identifies the role of typhoons in mitigating droughts through an analysis assuming a world without typhoons.