Kansas City University review highlights astrocytes as key drivers of chronic traumatic encephalopathy
Peer-Reviewed Publication
Updates every hour. Last Updated: 25-Oct-2026 11:16 ET (25-Oct-2026 15:16 GMT/UTC)
Researchers from Kansas City University School of Medicine have published a scoping review examining the role of astrocytes in chronic traumatic encephalopathy (CTE). Synthesizing evidence from 40 studies, the review suggests that astrocytic dysfunction, neuroinflammation, impaired waste clearance, and disrupted glutamate homeostasis may contribute significantly to disease development and progression. The findings support a shift from a neuron-centric view of CTE toward a broader neuroglial disease model.
Researchers at Queen Mary University of London have discovered that tiny photosynthetic bacteria band together into protective "herds" when attacked by predators – a survival strategy that could also influence how carbon is stored in the world's waters.
Elephants use air-transmitted sound to communicate with one another but also rely on ground vibrations to cover even larger distances. A new study focusing on elephants’ middle ear structure showed that their ears are more sensitive to low-frequency vibrations transmitted through bone than human ears. This sensitivity is thought to be due to elephant anatomy: their large and heavy middle ear bones can effectively transmit lower-frequency sounds to the inner ear. The study analysis also indicates that elephants’ ability to voluntarily close their ear canal may further improve their bone-conduction hearing. This later mechanism is similar to people hearing their own voice louder after putting in earbuds.
Why does the immune system become less effective as we age? A new USC study published in BMC Biology offers fresh insights by examining a key immune cell type across tissues: macrophages.
Macrophages act as the body’s cleanup and maintenance crew. Found in nearly every tissue, they help fight infections, remove damaged cells, repair tissues, and keep inflammation under control – acting as a first line of defense for the immune system. But like many cells in the body, macrophages change as we get older.
In this new study, researchers analyzed data from macrophages collected from different mouse tissues, including the brain, lungs, liver, and other organs. By comparing younger and older animals, they uncovered common patterns of aging shared across many macrophage populations, as well as important differences depending on where the cells come from.
Chronic pancreatitis, which affects around three million people worldwide, is especially difficult to treat because the molecular drivers of the disease vary from patient to patient. Salk researchers have created a new platform for studying chronic pancreatitis that retains patient-specific disease biology, which can be used to develop personalized chronic pancreatitis treatments and has already pinpointed a protein that could be a promising target for many patients.
A new tool that allows researchers to create realistic full-body animations of monkeys has provided the first evidence that non-human primates experience the “uncanny valley” phenomenon for body avatars, according to a study by Lucas Maximilian Martini at the University Clinic Tubingen in Germany and colleagues at KU Leuven in Belgium, publishing July 14th in the open access journal PLOS Biology.