A longitudinal metabolomics study of 28 patients with house dust mite-induced allergic rhinitis and 19 healthy controls found that plasma and nasal secretions capture distinct but complementary aspects of disease biology. After six months of clinically effective subcutaneous immunotherapy, both compartments shifted toward healthy profiles, but nasal metabolic recovery was more evident, revealing coordinated yet asynchronous systemic-local remodeling.

Coronary artery disease remains the top global cause of death, yet current clinical practice often targets advanced vessel narrowing and ischemia, missing opportunities for early prevention before heart attacks occur. This peer‑reviewed commentary, inspired by The Lancet Commission, synthesizes real‑world Chinese population data showing atherosclerotic plaques are common among middle‑aged and older adults, with coronary plaque prevalence reaching 44.9% in local community cohorts aged 50‑75 years. The authors outline a stepwise, risk‑stratified screening workflow for primary‑care settings to detect subclinical plaque, prioritize systemic medical therapy over routine stenting for non‑culprit unstable lesions, and integrate inflammation and environmental risk control. The authors note that robust long‑term randomized trial evidence is still needed to validate broad implementation of plaque‑guided care.

Summer break can bring changes in daily routines that make it harder for adolescents to maintain healthy habits. Researchers from Pennington Biomedical Research Center, FMOL Health | Our Lady of the Lake Children’s Health and LSU are exploring how technology can help keep adolescents engaged in healthy behaviors during and after a structured summer program.

A pilot study tested an eight-week summer health promotion program that combined an in-person camp with an AI-assisted mobile app, wearable activity trackers and personalized behavioral support.