Cracking the code of p53 fragility: Why the genome guardian is prone to failure
Peer-Reviewed Publication
Updates every hour. Last Updated: 31-May-2026 11:16 ET (31-May-2026 15:16 GMT/UTC)
Researchers at the Icahn School of Medicine at Mount Sinai and collaborators have discovered that many gut bacteria use a flexible survival strategy to withstand disruptions such as antibiotics and diet changes. Published in the May 19 online issue of Cell Host & Microbe (DOI: 10.1016/j.chom.2026.04.019), the study shows microbes can switch between functional states, rather than relying solely on genetic mutations, to try to survive shifting conditions. The findings shed light on a previously hidden layer of microbiome biology and may help explain why probiotics and fecal microbiota transplantation (FMT) produce inconsistent benefits across individuals.
A new study led by Dr Lin Su of Queen Mary University of London, published today in the Journal of the American Chemical Society, describes a new integrated solar reactor in which engineered Escherichia coli (E. coli) are grown directly inside the same liquid that converts CO₂ into a usable energy source using sunlight. In future, this technology may be used to make environmentally clean chemicals, plastics or even microbial protein.
Understanding the packing and folding of DNA in sperm cells is a fundamental question in modern biology, related to infertility and to genetic and developmental defects. UC Davis researchers have now unveiled an important new piece of this puzzle. They have identified a protein, called DAXX, that guides how sperm DNA is organized, silences numerous genes and keeps some switched on. The work was published recently in Genes & Development.
A new article (https://doi.org/10.1093/biosci/biag047) in the journal BioScience argues that the stewardship practices of Indigenous Peoples and other place-based knowledge holders have been systematically underrepresented in both conservation research and international policy along with the knowledge holders and practitioner themselves—and that correcting this imbalance is essential to more effective and equitable biodiversity governance.