A reconstructed protein interactome for the Last Eukaryotic Common Ancesor led researchers to identify hundreds of ancient genes that appear to be associated with human diseases. Follow-up experiments confirmed three of these gene-disease associations. The work could potentially lead to new targets for treating a host of other diseases.

Just in time for May, a research team led by Dirk Hoffmeister and Sebastian Dörner published a revised model of muscarine biosynthesis in Angewandte Chemie International Edition. The findings from this study could help improve the detection and treatment of mushroom poisoning.

A study led by researchers at the Universitat Autònoma de Barcelona (UAB) and the Josep Carreras Leukaemia Research Institute (IJC) has identified the Sirtuin 7 (SIRT7) protein as a new essential factor in maintaining the genome stability of male germ cells over time. The study, conducted with mice, is published in the journal Nature Communications. Researchers from Rutgers University (USA) have also participated.

Led by University of Tartu researchers, the largest and most comprehensive study to date has been completed on how genetic differences between individuals influence metabolism.

Researchers find surprising links which show that Neandertal ancestry influences our immune system today in ways more nuanced than previously recognised. 

Ascidians, also known as sea squirts, are the evolutionary link between vertebrates and invertebrates, making them valuable subjects of biological studies. For the first time, researchers at Ruhr University Bochum have detected pronounced autofluorescence in Halocynthia papillosa, one of over 3,000 species. Furthermore, the study provides comprehensive insights into the anatomy of this sea squirt. The study demonstrated the potential of modern, multimodal imaging—from light and confocal microscopy to MRT and high-resolution synchrotron tomography, which facilitates three-dimensional imaging of even low-contrast tissues. The study was published in the journal Communications Biology on April 22, 2026.

An international research team led by scientists from the Museum of Natural Sciences in Barcelona, the  Institute of Evolutionary Biology (IBE), a joint center of the Spanish National Research Council (CSIC) and Pompeu Fabra University (UPF), and the Max Planck Institute for Chemical Ecology in Jena, Germany, has discovered that the fire salamander (Salamandra salamandra) is biofluorescent. Their work, published in Royal Society Open Science, reveals that this iconic species emits turquoise light when exposed to ultraviolet radiation. This phenomenon had gone unnoticed despite decades of study.