New foundation model reveals how cells are organized in tissues
Peer-Reviewed Publication
Updates every hour. Last Updated: 30-Dec-2025 19:11 ET (31-Dec-2025 00:11 GMT/UTC)
Researchers at Helmholtz Munich and the Technical University of Munich (TUM) have developed Nicheformer, the first large-scale foundation model that integrates single-cell analysis with spatial transcriptomics. Trained on more than 110 million cells, it offers a new way to study how cells are organized and interact in tissues – knowledge that is crucial for understanding health and disease.
What audible components of animal communication serve an alerting function? A team of researchers from the University of Konstanz, Tel Aviv University and Bar-Ilan University have analyzed whether the so-called wails, which initiate rock hyraxes’ songs, serve that purpose. They published their results in the journal Animal Behaviour.
- Science learns from nature's methods
- Potential benefits for future therapies against cancer and Alzheimer's disease
- Joint research by TUM and Helmholtz Munich
In the fight against disease, programmed cell death – also known as apoptosis – is a key protective function of the body. It breaks down cells that are damaged or have undergone dangerous changes. However, cancer cells often manage to override this mechanism. A research team at the Technical University of Munich (TUM) has now succeeded in identifying a new molecular switch in this process and elucidating how it works.
New research shows that modern agriculture is impacting biodiversity inside protected areas in Europe, while some traditional agricultural practices may help preserve it. The Natura 2000 is the largest network of protected areas in the world, established to conserve the most valuables habitats and species in the European Union (EU). Researchers conducted a large-scale survey among Natura 2000 protected area managers across all Europe focusing on management practices, funding and threats to biodiversity facing the Natura 2000 network.