EurekAlert! News by Subject: Chemistry & Physics - News by Subject: Chemistry & Physics

Chemistry & Physics

Updates every hour. Last Updated: 29-Aug-2025 05:11 ET (29-Aug-2025 09:11 GMT/UTC)

Comprehensive chemical analysis of codonopsis lanceolata roots and the vasodilatory effects of its major compound, lancemaside A

Toho University
Peer-Reviewed Publication

A research group led by Associate Professor Takashi Kikuchi and Professor Wei Li from the Department of Pharmacognosy at the Faculty of Pharmaceutical Sciences, Toho University, along with Professor Atsushi Sugiyama from the Department of Pharmacology at the Faculty of Medicine and Industry-Academia Collaboration Advisor Katsuhiko Ito, has analyzed the chemical compounds of the roots of Codonopsis lanceolata (commonly known as “Tsuruninjin”) grown in Nagano Prefecture. Their findings have revealed the compounds of the plant and, in particular, demonstrated that its major compound, lancemaside A, exhibits vasodilatory effects, suggesting that Codonopsis lanceolata could be effectively utilized as a health-promoting material in the future.

This research was published in the academic journal Chemistry on January 6, 2025.

Journal: Chemistry
Funder: Japan Society for the Promotion of Science

NUS Medicine study: Breaking antibiotic-resistant bacteria’s protective shields opens door for immune system response, offers insights for managing pneumococcal diseases

National University of Singapore, Yong Loo Lin School of Medicine
Peer-Reviewed Publication

Antibiotic-resistant bacteria is a serious public health threat. Understanding the biology of these bacteria—such as how they synthesise their protective capsules—is essential for developing new strategies to counter antibiotic resistance.

Journal: Science Advances

Guardians of the vineyard: Canines and chemistry work to combat powdery mildew

American Chemical Society
Reports and Proceedings

Dogs have many jobs but one you may not expect is identifying grapevines with a destructive and highly contagious fungus called powdery mildew. Researchers are analyzing volatile chemicals emanating from grape leaves infected by powdery mildew, with the goal of improving training for vineyard canines. The researchers will present their results at ACS Spring 2025.

Meeting: ACS Spring 2025

Improving GLP-1 drug delivery by ‘painting’ it on antibodies

American Chemical Society
Reports and Proceedings

GLP-1 receptor agonists are peptide-based drugs used for managing diabetes and for weight loss, but these treatments have had shortages recently. Now, through a process called in vivo antibody painting, researchers have attached GLP-1 receptor agonists to antibodies through a reaction that happens inside the body, increasing the drug’s stability. In animal models, a single dose works better and lasts longer than currently administered dosages. The researchers will present their results at ACS Spring 2025.

Meeting: ACS Spring 2025

Results of the INHALE-3 extension study: inhaled technosphere insulin plus insulin degludec in T1D

Mary Ann Liebert, Inc./Genetic Engineering News
Peer-Reviewed Publication

New Rochelle, NY, March 20, 2025—A new study in the peer-reviewed journal Diabetes Technology & Therapeutics (DTT) evaluated the effects of a regimen of inhaled technosphere insulin (TI) and insulin degludec over 30 weeks and its potential to reduce post-meal hyperglycemia in adults with type 1 diabetes.

Journal: Diabetes Technology & Therapeutics

IU professor helps pioneer groundbreaking light-driven method to create key drug compounds

Indiana University
Peer-Reviewed Publication

Researchers at Indiana University and Wuhan University in China have unveiled a groundbreaking chemical process that could streamline the development of pharmaceutical compounds, chemical building blocks that influence how drugs interact with the body.

Journal: Chem

Can electricity flow without electrons?

DOE/US Department of Energy

Scientists have long held that electricity is carried by individual electrons with discrete charges moving in a metal, even in the case of electrons clumped into quasiparticles. However, “strange metals” fail to obey this paradigm. Researchers have observed a radical quantum blurring of electrons in strange metal into a featureless liquid, potentially pointing toward a new theory of electrical transport.

Journal: Science