Selective boron-heteroatom group exchange reactions
Peer-Reviewed Publication
Updates every hour. Last Updated: 22-Oct-2025 21:11 ET (23-Oct-2025 01:11 GMT/UTC)
De-Wei Gao's research group at ShanghaiTech University has developed a new method for efficient and highly selective boron-heteroatom functional group exchange reactions. Their method overcomes the inherent difficulty of primary radical instability in traditional free radical chemistry and can achieve highly selective conversion of primary carbon-boron bonds to a variety of heteroatom functional groups. This strategy has been successfully applied to a sugar-derived 1,n-diboron compound system, achieving modular modification and efficient synthesis of sugar molecules and has shown to have potential application in the rapid construction of bioactive molecules. These results were published as an open access article in CCS Chemistry, the flagship journal of the Chinese Chemical Society.
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