Sustainable nitrogen transformation is central to clean energy development, environmental protection, and future chemical manufacturing. This study summarizes major advancements in designing metal–organic framework–nanoparticle (MOF–NP) composite catalysts that accelerate key nitrogen electrochemical reactions under mild conditions. By integrating the structural tunability and porosity of metal–organic frameworks MOFs with the conductivity and catalytic activity of nanoparticles, these hybrid materials significantly improve nitrogen reduction, nitrate reduction, and ammonia oxidation. The analysis highlights how MOF–NP interfaces enhance reaction selectivity, stabilize intermediates, increase Faradaic efficiency, and support strong long-term durability. Together, these performance gains position MOF–NP composites as promising candidates for green ammonia synthesis, nitrate remediation, and next-generation nitrogen-based energy systems.

This review highlights how natural polysaccharide-based microneedles (PMNs) are emerging as a transformative platform for cancer immunotherapy. We report their unique dual role in drug delivery and immune regulation, the innovative use of 3D printing for precision fabrication, and their smart responsiveness to the tumor environment. By integrating biocompatibility, enhanced drug loading, and controlled release, polysaccharide-based microneedles (PMNs) offer a promising strategy to overcome challenges in traditional cancer immunotherapies, potentially supporting the development of more effective and personalized treatments.

Scientists have developed a novel Cr-based single-atom catalyst that enables highly efficient hydrogen peroxide (H₂O₂) production in acidic environments through an electrochemical process. This breakthrough, guided by molecular dynamics simulations, reveals a self-adjusting mechanism with the catalyst actively restructuring during the reaction, achieving exceptional selectivity that rivals or even surpasses that of conventional Co-based catalysts.

Scientists in China have engineered topology-driven energy transfer networks in lanthanide-doped upconversion nanoparticles to dramatically reduce the laser power needed for stimulated emission depletion (STED) microscopy. By spatially separating sensitizers and emitters in core–shell nanoparticles, they enhanced energy migration, boosted emission, and improved optical switching efficiency. Their design achieves STED microscopy imaging with significantly lower excitation and depletion intensities, paving the way for low-power, photostable super-resolution imaging in life sciences and nanophotonics.