Scientists uncover new on-switch for pain signaling pathway that could lead to safer treatment and relief
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Updates every hour. Last Updated: 20-Nov-2025 19:11 ET (21-Nov-2025 00:11 GMT/UTC)
A patented RNA-based cocktail developed at the Italian Institute of Technology (IIT-Istituto Italiano di Tecnologia) has emerged as a promising active agent against tumors of the central nervous system, such as glioblastoma. The study, published today in the scientific journal Molecular Therapy – Nucleic Acids, demonstrates the effectiveness of a combination of 11 different non-coding RNAs, known as microRNAs (miRNAs), in slowing the growth of cancer cells and enhancing the activity of chemotherapeutic drugs. Tests were carried out on patient-derived cells and on preclinical models. Further validation steps will be required for medical use of the compound.
Organizations across the nation recognized National Injury Prevention Day (NIPD) on November 18th, a day to increase awareness about the burden of injuries and violence, the leading cause of death and hospitalization for Americans ages 1-44. Through education, advocacy, and collaboration, NIPD empowers individuals and communities with the knowledge and tools to prevent injuries and promote safety for all.This nationwide initiative, now in its sixth year, is led by the Injury Free Coalition for Kids®, based in the Columbia Center for Injury Science and Prevention (CCISP) at Columbia University Mailman School of Public Health.
A combination of outreach methods – including texts, automated messages, and live phone calls – can significantly improve follow-up care for hard-to-reach patients after they have been discharged, according to a new nursing study from UCSF Health.