Insilico Medicine (“Insilico”; HKEX: 3696), a clinical-stage generative artificial intelligence (AI)-driven drug discovery company, today announced Longevity Vaccines, a research initiative developing treatments that direct a patient’s own immune cells to eliminate the earliest cellular drivers of age-related disease. This initiative expands the company’s dual-purpose, aging-oriented discovery strategy from small molecules into RNA-encoded, in vivo cell engineering. 

Non-fatal overdoses happen far more often than fatal overdoses, yet little is known about where they occur. A study of 1,661 non-fatal overdoses in Palm Beach County found that nearly half of mapped overdose hotspots significantly overlapped with gas stations, while others followed major transportation corridors. Nearly 40% of overdoses occurred outdoors, with outdoor overdoses strongly associated with housing instability, lack of insurance and younger age. People experiencing housing instability had five times the odds of overdosing near a gas station, offering new opportunities for targeted, place-based prevention.

Published in the International Journal of Extreme Manufacturing, researchers improved the balance of strength and ductility by using laser powder bed fusion to create alternating coarse- and fine-grained regions in a zinc–copper alloy.

Patients with major depressive disorder (MDD) and an inadequate response to standard antidepressants who received an add- on treatment with the drug lumateperone saw significantly improved sexual function, found a new study led by a University of Virginia School of Medicine researcher.