Association of sarcopenia with the long-term risk of overall infections and infectious diseases: a prospective cohort study of 458 332 participants
Peer-Reviewed Publication
Updates every hour. Last Updated: 25-Oct-2026 12:16 ET (25-Oct-2026 16:16 GMT/UTC)
Sarcopenia, the age-related loss of muscle mass and function, has been associated with various adverse health outcomes. However, its relationship with infection risk remains unclear. This prospective cohort study of 458,332 participants from the UK Biobank examined the association between sarcopenia and the long-term risk of overall infections and specific infectious diseases. Our findings highlight the importance of maintaining muscle health for immune function and infection prevention. The study provides new evidence for the role of sarcopenia as a modifiable risk factor for infectious disease susceptibility.
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