Core2Edge: How tumor cells conquer the brain
Peer-Reviewed Publication
Updates every hour. Last Updated: 25-Oct-2026 18:16 ET (25-Oct-2026 22:16 GMT/UTC)
Glioblastoma is an aggressive brain tumor that infiltrates deep into the surrounding brain tissue. Even after surgery, tumor cells remain in the brain and the tumor recurs. Researchers at the University Hospital Bonn (UKB) and the University of Bonn have now developed Core2Edge, a model based entirely on human tissue that captures these hard-to-access infiltration zones at the tumor margin. The model enables investigation of the invasive front and direct assessment of new drug candidates in human tissue - without the need for animal testing. The study of the Brain Tumor Translational Research Group has now been published in Nature Protocols.
With the widespread adoption of 5G communication and smart devices, electromagnetic radiation and interference have become critical issues affecting electronic equipment operation and human health. A research team led by Professor Guanglei Wu and Associate Professor Zirui Jia from Qingdao University has developed a novel CoS2/NiS2@HCNFs composite material. By employing an innovative strategy that combines bimetallic sulfide heterointerfaces with sulfur vacancies, they have successfully resolved the core challenge of balancing impedance matching and loss capability in traditional electromagnetic wave (EMW) absorbing materials. This material achieves an ultra-wide absorption bandwidth of 10.08 GHz at a minimal thickness of 2.6 mm, representing a 61% performance improvement over single-metal systems. It offers a lightweight, high-efficiency solution for electromagnetic protection, stealth technology, and 5G device shielding.
A research paper by scientists at Zhejiang University examined whether exposure to heatwaves (HWs) is linked to more rapid biological aging in adults of middle and advanced age.
The research paper, published on Jul 15, 2026 in the journal Cyborg and Bionic Systems.
What makes a diet healthy—or not? According to a new study, nutritional quality matters more than processing level when it comes to long-term health. The study of over 200,000 people found that the overall quality of a person’s diet was strongly associated with their risk of heart disease, type 2 diabetes, and death. However, these associations did not appear to substantially differ based on food processing levels.
Researchers from the Universities of Hildesheim, Bonn, and Freiburg have now uncovered how human skeletal muscle responds to resistance exercise at the molecular level. Their findings provide new insights that could help optimize training programs for athletes, improve rehabilitation strategies, and counteract age-related muscle loss. Resistance training is essential for maintaining healthy skeletal muscle throughout life. The World Health Organization now recommends moderate muscle-strengthening activities at least twice a week, even for older adults, to help prevent the loss of muscle strength. The new study is published in the latest issue of Nature Communications.
Osteoporosis affects millions of people worldwide, weakening bones and increasing the risk of fractures. Now, researchers have identified the AXL receptor tyrosine kinase (Axl) as a key molecule that limits the activity of bone-forming cells. Blocking Axl with a small-molecule inhibitor increased bone formation and bone mass in mice while revealing how the receptor controls bone development. These findings could support the development of more accessible treatments for osteoporosis and other bone diseases.
Presentation to feature first-in-human results for ISM6331, a novel, AI-designed pan-TEAD inhibitor targeting the Hippo pathway
Global Phase 1 multicenter study evaluates safety, tolerability, and preliminary efficacy in patients with mesothelioma and other advanced solid tumors