Targeting mitochondria could open new routes to personalized treatment for triple-negative breast cancer
Peer-Reviewed Publication
Updates every hour. Last Updated: 21-Oct-2026 13:16 ET (21-Oct-2026 17:16 GMT/UTC)
A deeper understanding of mitochondrial function could create new opportunities for treating triple-negative breast cancer (TNBC), one of the most aggressive and difficult-to-treat forms of breast cancer. The complex relationship between mitochondrial dynamics, energy metabolism and cancer-cell survival is revealing potential targets that could support more personalized treatment strategies.
A new review published in Genes & Diseases highlights the expanding potential of DNA-based vaccines as a flexible platform for preventing infectious diseases, treating cancer and strengthening preparedness for future disease outbreaks. The article charts the evolution of DNA vaccination from early concepts in the 1990s to increasingly sophisticated technologies with applications across infectious disease, oncology and precision medicine.
A research “super team” co-led by the Buck Institute for Research on Aging and Georgetown University has received an award of up to $51.7 million from the Advanced Research Projects Agency for Health (ARPA-H) to predict how disease-causing proteins misfold before irreversible damage occurs and use those predictions to develop novel diagnostics and treatments. The four-year effort is expected to lead to new ways of detecting, slowing and treating neurodegenerative diseases and cancer, with an initial focus on Alzheimer's disease and Ewing sarcoma.