Chronic alcohol use reshapes gene expression in key human brain regions linked to relapse vulnerability and neural damage
Peer-Reviewed Publication
Updates every hour. Last Updated: 28-May-2026 15:15 ET (28-May-2026 19:15 GMT/UTC)
Analyzing post-mortem brain tissue from individuals with alcohol use disorder, researchers identified significant changes in genes of the endocannabinoid system within the prefrontal cortex and nucleus accumbens. Published in Addiction, the study helps explain impaired impulse control and relapse vulnerability in alcoholism. It also highlights new molecular targets for more effective, personalized treatments.
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A new study conducted during the Israel-Hamas war reveals that a teacher's subjective sense of stress and helplessness is a far stronger predictor of burnout than their actual physical exposure to war-related events. By surveying 329 Jewish and Arab educators, the research identified "cognitive reappraisal," the ability to mentally reframe difficult situations, as a vital protective factor that lessens the impact of war exposure on professional exhaustion. These findings suggest that personal resilience can be strengthened through targeted workshops, helping teachers maintain their mental health and efficacy during chronic national crises.