Global heterogeneity and implementation gap in acute kidney injury prevention in ICUs: Results from the international AKI-PURIFY survey
Peer-Reviewed Publication
Updates every hour. Last Updated: 26-Oct-2026 23:16 ET (27-Oct-2026 03:16 GMT/UTC)
A new AI model called COMPASS uses tumor gene expression data to predict which patients will respond to cancer immunotherapy drugs called immune checkpoint inhibitors. Analyzing past data from 16 clinical cohorts, COMPASS predicted ICI response 8.5 percent more accurately than the best existing approach. If validated in clinical trials, the tool could lead to better precision medicine and cancer drug development.
Published in The Lancet, results of the phase III COMPETE clinical trial show that the targeted radiotherapeutic agent [177Lu]Lu-edotreotide significantly prolonged progression-free survival in patients with metastatic gastroenteropancreatic neuroendocrine tumors (GEP-NETs) when compared to targeted therapy with everolimus.
In a post hoc analysis of 210 ICU-admitted patients from the French multicenter COMBAT cohort, nearly half of survivors of community-acquired bacterial meningitis still had unfavourable functional outcomes 1 year after intensive care. Hearing loss, depressive symptoms, and impaired physical quality of life were common, while fewer than half resumed work. The SOFA score on day 3 independently predicted 30-day mortality, highlighting the value of repeated organ function assessment.
A UTHealth Houston neurologist was among a group of two dozen healthcare professionals from across the globe who developed an international certification program designed to improve rehabilitation care among stroke survivors.