28-Jun-2026
Mini monitor measures artificial heartbeat
University of TokyoPeer-Reviewed Publication
An international team, including the University of Tokyo, has created a sensor inspired by the lateral line in fish – their “sixth sense” organ – which measures the pulse of lab-grown 3D heart tissue (cardiac organoids). The device, called a biomechanical well plate, looks like a small white box containing four liquid-filled wells. When an organoid is placed in a well, each beat causes the liquid to bulge into an air cavity below, changing the air pressure. This change bends a cantilever sensor, which sends live data wirelessly to an app. The device is precise, reusable and less labor-intensive than some other methods. Due to its scalability, hundreds of tests could potentially be monitored simultaneously, with advantages for drug screening and future personalized medicine.
- Funder
- Australian Research Council, National Health and Medical Research Council, We acknowledge support from NSW’s Non-Animal Technologies Network (NAT NET) for the development of 3D bioengineered tissue models, the Victor Chang Cardiac Research Institute Innovation Centre, funded by the NSW Government., We also acknowledge support from NSW Health/Cardiovascular Research Capacity Program – Senior and Early-Mid Career Researcher Grants (RG242730) funded by the NSW Government, the Cancer Institute NSW Career Development Fellowship (PS66730)., This work was performed in part at the NSW Node of the Australian National Fabrication Facility at the University of New South Wales.