Discovery of SARS-CoV-2 PLpro inhibitors and RIPK1 inhibitors with synergistic antiviral efficacy in a mouse COVID-19 model
Peer-Reviewed Publication
Updates every hour. Last Updated: 18-Jun-2026 05:16 ET (18-Jun-2026 09:16 GMT/UTC)
https://doi.org/10.1016/j.apsb.2025.09.026
This new article publication from Acta Pharmaceutica Sinica B, discusses the discovery of SARS-CoV-2 PLpro inhibitors and RIPK1 inhibitors with synergistic antiviral efficacy in a mouse COVID-19 model.
https://doi.org/10.1016/j.apsb.2025.10.031
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https://doi.org/10.1016/j.apsb.2025.10.005
This new article publication from Acta Pharmaceutica Sinica B, discusses the deep learning-based discovery of tetrahydrocarbazoles as broad-spectrum antitumor agents and click-activated strategy for targeted cancer therapy.
https://doi.org/10.1016/j.apsb.2025.09.014
This new article publication from Acta Pharmaceutica Sinica B, discusses the construction of a localized immune niche via supramolecular hydrogel vaccine to elicit durable and enhanced immunity against infectious diseases.
https://doi.org/10.1016/j.apsb.2025.11.016
This new article publication from Acta Pharmaceutica Sinica B, discusses how Chinese medicine and intermittent fasting integration therapy attenuate diabetic vascular calcification via miR21-5p/Tpm1-mediated osteogenic differentiation of VSMCs.
https://doi.org/10.1016/j.apsb.2025.10.006
This new article publication from Acta Pharmaceutica Sinica B, discusses how an innovative and stable mRNA-LNP microneedle vaccine elicits humoral and multifunctional cellular immune responses.
https://www.sciencedirect.com/journal/acta-pharmaceutica-sinica-b/vol/16/issue/1
Acta Pharmaceutica Sinica B (APSB) was founded with the goal of creating a global high-level forum centred around drug discovery and pharmaceutical research/application. APSB was included by Chemical Abstracts in 2011, accepted by PubMed Central in 2015, indexed by Science Citation Index in 2017 and has evolved to become one of the most important international journals in the field of pharmaceutical sciences.