Breast cancer can remain dormant in the bone marrow for decades before reactivating, resulting in cancer relapse. A study published in Bone Research unveils the critical role of Notch2 signaling pathway in promoting this dormant state. The study explains how dormant cancer cells mimic healthy stem cells and activate stress pathways to survive in the bone marrow—paving the way for innovative targeted therapies against dormant cancer cells.

Non-structural disaster measures, including early warnings and evacuation systems, helped improve coastal resilience and reduce storm-surge impacts in Macau, report researchers at Science Tokyo. After analyzing the city’s responses to three major typhoons, which included resident interviews, evaluations of early warning systems, evacuation procedures, and other typhoon mitigation efforts, the study found that earlier issuance of typhoon warnings, color-coded storm-surge alerts, and government-led evacuation guidance significantly improved public trust and reduced disaster impacts.

The goal of merging intelligent computers directly with the human body, whether for continuous health monitoring or controlling advanced prosthetics, has long been stalled by a fundamental physical conflict. A new review article in the International Journal of Extreme Manufacturing details how purely rigid architectures are shifted toward soft, brain-inspired electronics that can sense, store, and process information while mechanically conforming to biological tissues.