Lactate IV infusion found to trick the body into releasing a hormone behind that post-workout brain boost
Peer-Reviewed Publication
Updates every hour. Last Updated: 18-Jan-2026 08:11 ET (18-Jan-2026 13:11 GMT/UTC)
Exercise is known to ultimately boost the release of brain-derived neurotrophic factor (BDNF), a hormone essential for brain health. One trigger for the underlying cascade is thought to be increasing lactate in the blood, produced by skeletal muscle through the oxygen-poor metabolism that is typical of high-intensity exercise. Now, sports scientists have shown for the first time that an IV infusion with lactate is sufficient to stimulate the release of the biologically active precursor molecule pro-BDNF. So while this might be enough to trigger the release of a brain-boosting hormone without exercising, researchers warn it’s not an excuse not to make that morning run.
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