Using lung cancer biospecimens from the Sherlock-Lung study, an international team led by National Institutes of Health (NIH) researchers, identified key factors that drive tumor evolution and influence outcomes. Overall, the findings, published Dec. 10, 2025, in Nature, describe a previously unknown origin of some aggressive lung cancers. 

A molecule involved in red blood cell production determines whether the immune system attacks or ignores cells in the body via peripheral immune tolerance, Stanford Medicine-led research finds.

About The Study: In this cohort of patients with type 2 diabetes, glucagon-like peptide 1 receptor agonist (GLP-1 RA) use was associated with significantly lower risks of vertebral compression fractures and related surgical interventions compared with nonuse, suggesting bone protective benefits of GLP-1 RAs. 

About The Study: Consistent with prior work, this study found low adherence (7.3%) to cervical cancer screening guidelines among the commercially insured U.S. population despite stable coverage, likely reflecting guideline confusion among patients, clinicians, and health systems. More evidence-based strategies are needed to expand capacity for guideline-adherent screening, reduce over-screening, and align payer and health system incentives, particularly as new modalities, such as human papillomavirus (HPV) self-sampling, emerge.

In a pilot study, researchers from North Carolina State University have found a novel kirkovirus that may be associated with colitis – and potentially small colon impactions – in horses. The study could offer a route to new therapies for horses with colitis symptoms from unknown causes.

Alexandria, VA – A new article published in the Journal of Dental Research explores the development an integrated data-cleaning and subtype discovery pipeline using unsupervised machine learning for comprehensive analysis and visualization of data patterns in the National Health and Nutrition Examination Survey (NHANES) database.

Casey Taft, PhD, professor of psychiatry at Boston University Chobanian & Avedisian School of Medicine, has been awarded the Barbara Thompson Excellence in Research on Military and Veteran Families Award for his military research paper, “Examining Strength at Home Couples to Prevent Intimate Partner Violence on a Military Installation: A Randomized Controlled Trial.”