A new study published in the journal Nature Genetics maps out the timeline of DNA damage for multiple myeloma. The findings may lead to better ways to group patients by the state of their DNA and define new subtypes of disease to better predict treatment strategies and outcomes.

Researchers from Kumamoto University have identified a distinctive CT imaging pattern that can predict which women experiencing severe postpartum hemorrhage (PPH) are most likely to need life-saving interventions. The new finding, termed PRACE (Postpartum hemorrhage, Resistance to treatment, and Arterial Contrast Extravasation), was observed in nearly one-third of patients undergoing dynamic CT scans and was strongly associated with the need for emergency procedures such as uterine artery embolization.

A new study finds that a high-salt diet triggers brain inflammation that drives up blood pressure.

The research, led by McGill University scientist Masha Prager-Khoutorsky in collaboration with an interdisciplinary team at McGill and the Research Institute of the McGill University Health Centre, suggests the brain may be a missing link in certain forms of high blood pressure – or hypertension – traditionally attributed to the kidneys.

The move raised concerns about harmful mutations and genetic swamping — or loss of unique traits. However, a recent study co-authored by UCF Assistant Professor of Biology and Genomics and Bioinformatics faculty cluster member Robert Fitak, found that since the introduction, genetic variation has significantly improved; unique traits have been retained; and harmful mutations, while still present, are largely masked by the restored genetic variation.

Researchers found that mitochondrial dysfunction in the blood-brain barrier (BBB) may lead to neuropsychiatric disease in some patients with 22qDS. The researchers also demonstrated that a class of FDA-approved cholesterol drugs could potentially be repurposed to treat this dysfunction.