Researchers uncover new role of mutant proteins in some of the deadliest cancers
Peer-Reviewed Publication
Updates every hour. Last Updated: 1-May-2025 11:08 ET (1-May-2025 15:08 GMT/UTC)
Researchers at the National Institutes of Health (NIH) and their collaborators have discovered a new way in which RAS genes, which are commonly mutated in cancer, may drive tumor growth beyond their well-known role in signaling at the cell surface. Mutant RAS, they found, helps to kick off a series of events involving the transport of specific nuclear proteins that lead to uncontrolled tumor growth, according to a study published November 11, 2024, in Nature Cancer.
A small survey of adults aged 30 to 89 (average age of 65) in Sweden who have heart conditions found that there is a significant difference between the sexual health information they seek and what is provided to them by their health care professionals and the health care system. Despite 76% of patients with heart conditions reporting that sexual health affects their mood and well-being, only 5% received information or counseling about sexual health.
Scientists conducted a simulation study to estimate the impact of cardiovascular-kidney-metabolic (CKM) syndrome on cardiovascular disease (CVD) risk prediction. The study found that adults with chronic kidney disease would have elevated CVD risk eight years earlier than those without the disease. In addition, people with Type 2 diabetes would have an elevated CVD risk about a decade sooner than those without it.
In a paper published in Science China Life Sciences, professor Wang Guoqing's team at Jilin University conducted single-cell sequencing analysis on right ventricular free wall tissue from healthy donors and patients with characteristic coagulation abnormalities of COVID-19, revealing the mechanism of cardiac microthrombosis formation in patients after SARS-CoV-2 infection.
In a study led by researchers at the NUS Yong Loo Lin School of Medicine, extracellular vesicles (EVs) loaded with customisable anti-cancer antisense oligonucleotides suppressed cancer growth.