When the clocks stop changing: What time is best for health?
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Updates every hour. Last Updated: 23-Oct-2026 03:16 ET (23-Oct-2026 07:16 GMT/UTC)
A paper published in National Science Review brings together evidence on how plastics are produced, released, transported and transformed, and how they affect ecosystems, human health and Earth-system processes. It argues that lasting solutions must address the full plastics life cycle, with upstream prevention and safer design supported by reuse, recycling, pollution control, monitoring, and coordinated global governance.
A team led by researchers at Peking University Cancer Hospital & Institute reports that combining targeted KRAS inhibition with CTLA-4 immune checkpoint blockade overcomes the immunosuppressive microenvironment that renders KRAS-mutant gastric adenocarcinoma resistant to PD-1 immunotherapy. In a genetically faithful, immunocompetent mouse model of KRASG12D-driven gastric cancer, the combination suppressed TGF-beta signaling, impaired regulatory T cell function and elicited effective anti-tumor immunity. The study, published in Science China Life Sciences, provides a preclinical rationale for CTLA-4-based combination immunotherapy in this molecularly defined subset of patients.
Tony Hunter receives the 2026 Albany Prize in Medicine and Biomedical Research in recognition of his tyrosine phosphorylation discovery in 1979, which paved the way for 100+ cancer drugs. The award celebrates scientists whose research has led to treatments that significantly improve patients’ lives and comes with a $500,000 prize.