Hideyuki Okano starts new position as president of the ISSCR
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Updates every hour. Last Updated: 23-Dec-2025 02:11 ET (23-Dec-2025 07:11 GMT/UTC)
A collaborative multidisciplinary team of researchers from the Perelman School of Medicine and New York University has developed a miniature chip that could transform how blood cancer treatments are tested and tailored for patients. “This device addresses a significant gap in preclinical research, offering an advanced tool for studying CAR T cell therapy’s dynamic and multifaceted responses to leukemia,” says Saba Ghassemi of the Perelman School of Medicine at the Unviersity of Pennsylvania.
Relapsed/refractory peripheral and cutaneous T-cell lymphomas (R/R PTCL and CTCL) are aggressive blood cancers that often resist standard therapy. Patients with these lymphomas may require stem cell transplants, but the disease needs to be brought under control before patients can undergo this treatment. A new study by investigators from PETAL Consortium at Mass General Brigham found the combination of duvelisib and romidepsin to be effective, tolerable and safe for patients with R/R PTCL and CTCL. Their findings suggest that this drug combination offers a novel strategy to help these patients control the disease in order to be eligible for stem cell transplants. The results are published in Blood Advances.