A new medical large language model (LLM) achieved over 91 percent accuracy in identifying female participants diagnosed with major depressive disorder after analyzing a short WhatsApp audio recording where participants described their week, according to a study published January 21, 2026 in the open-access journal PLOS Mental Health by Victor H. O. Otani, from Santa Casa de São Paulo School of Medical Sciences and Infinity Doctors Inc., Brazil, and colleagues.

Ancient people transported a wild relative of the common potato across the southwestern U.S., likely expanding the range of the species, according to a study published January 21, 2026 in the open-access journal PLOS One by Lisbeth Louderback from the University of Utah, U.S., and colleagues. This research provides new evidence that Indigenous people may have put the species on a path to domestication, while creating a unique cultural element in the Four Corners region.

The presence of S. jamesii starch on tools, combined with earlier genetic, ecological, and ethnographic research, indicates that Indigenous people intentionally transported, cultivated, and managed the plant across the Four Corners region. These activities define an “anthropogenic range” created through extensive trade networks and long-term use, a key indicator of early domestication.