Yale genome engineers expand the reach and precision of human gene editing
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Updates every hour. Last Updated: 18-Jun-2025 10:10 ET (18-Jun-2025 14:10 GMT/UTC)
The promise of genome editing to help understand human diseases and create new therapies is vast, but technological limitations have limited advancement of the field. While existing editing technologies can alter or delete single base pairs within the human genome’s 3 billion base pairs, they are limited in their ability to alter multiple locations simultaneously — and can sometimes incorrectly alter neighboring DNA bases.
A new Yale study, however, advances the ability of scientists to edit multiple DNA sites by threefold and helps prevent unwanted mutations in nearby genetic sites.
The findings are published in the journal Nature Communications.
AI puts doctors in a bind, says Shefali Patil, associate professor of management at Texas McCombs, in a recent article. Health care organizations are increasingly pushing them to rely on assistive AI to minimize medical errors. But they lack direct support for how to use it.
The result, Patil says, is that physicians risk burnout, as society decides whom to hold accountable when AI is involved in medical decisions. Paradoxically, they also face greater chances of making medical mistakes.
Fungi have been around for many millions of years, with the incremental process of evolution honing and improving their survival skills through the millennia. Now, researchers at Binghamton University, State University of New York are studying the cell structure of fungi to learn how it determines their mechanical properties and what science can learn from that to create better materials.
A University of Houston optometry professor, who has pioneered the method of wearing multifocal lenses to slow myopia, is now reporting the biological changes associated with slowing eye growth when wearing multifocal lenses.