Traditional IHC requires one tissue section per stain, exhibits section-to-section variability, and incurs high costs and laborious staining procedures. While multiplexed immunohistochemistry (mIHC) techniques enable simultaneous staining with multiple antibodies on a single slide, they are more tedious to perform and are currently unavailable in routine pathology laboratories. Here, we present a deep learning-based virtual multiplexed immunostaining framework that simultaneously generates ERG and PanCK, in addition to H&E virtual staining, enabling the accurate localization and interpretation of vascular invasion in thyroid cancers.

A robot developed by NASA in preparation for missions to Mars is returning to the USA following a decade at the University of Edinburgh.

Demon Slayer, a well-known anime depicting a bamboo muzzle worn by a character, has been investigated from various perspectives. However, its scientific perspective particularly the depiction of bamboo muzzle remains unexplored. To fill this gap, a new study compared the lengths of bamboo segments shown in anime illustrations with measurements from real plants and mathematical models. The findings reveal major differences in the structure of anime bamboo and actual bamboo, enhancing public understanding about bamboo.

Scientists in China have developed a metasurface platform that realizes true three-dimensional (3D) vectorial holography by independently engineering the intensity and polarization of light along the propagation direction. By encoding volumetric information into structured beam arrays, the system enables high-fidelity 3D reconstruction and a new physical-layer optical encryption strategy based on the depth and polarization keys. This compact technology opens promising opportunities for secure communication, optical storage, and next-generation 3D displays.

Satellite navigation systems underpin modern society, supporting aviation, transportation, telecommunications, and scientific monitoring.