Researchers identify previously uncharacterized gene necessary for DNA repair
Peer-Reviewed Publication
Updates every hour. Last Updated: 20-Jun-2025 22:10 ET (21-Jun-2025 02:10 GMT/UTC)
In a new study, researchers from Boston University Chobanian & Avedisian School of Medicine, Massachusetts General Hospital (MGH) and Harvard Medical School, identified several uncharacterized chromatin factors (proteins that regulate gene expression) that are recruited to sites of DNA damage, including the gene ZNF280A. Importantly, this gene is hemizygously deleted – meaning one of the two copies of alleles is missing—in a subset of patients with a human developmental syndrome called 22q11.2 distal deletion syndrome.
Simultaneously detecting multiple signals with high precision has long challenged microelectromechanical systems (MEMS) sensors due to unavoidable interference.