A new artificial intelligence-driven pipeline developed in a collaborative research combines protein structure prediction, sequence design, and live-cell screening together to enable rapid conversion of antibody sequences into functional intracellular antibodies (intrabodies) that are stable within living cells. By preserving antigen-binding regions and improving structural stability, the approach overcomes major barriers encountered in intrabody development—emerging as a simpler, more cost-effective tool for diagnostics, imaging, and biomedical research.

Cooperation exists in board games, among researchers and among bacteria. Working closely together locally, scientists have deciphered how two species of bacteria join forces to avoid being eaten.