A joint research team from China Pharmaceutical University, Chinese Academy of Agricultural Sciences, National Engineering Research Center for the Emergency Drug, and Shandong Agricultural University has developed a novel multisite bridging‑mediated lateral flow immunoassay (mbLFIA) that enables ultrasensitive, enzyme‑free, visual on‑site detection of mosquito‑borne viruses such as chikungunya virus (CHIKV). The breakthrough, published in Targetome, addresses a critical global need for field‑deployable diagnostics in resource‑limited regions, where conventional nucleic acid tests rely on bioenzymes and bulky laboratory instruments.

A novel metabolic engineering strategy enhances riboflavin production by manipulating intracellular guanine levels through transporter engineering, demonstrating that overexpression of the NupG transporter can increase riboflavin titers by 15.3%.

A comprehensive genetic toolkit was developed for engineering Streptococcus species, addressing a critical need for better regulatory tools in these industrially important lactic acid bacteria. The study introduces short synthetic promoters and efficient sRNA-based repressors that enable streamlined control of gene expression.