In a groundbreaking study, researchers have captured real-time "molecular movies" showing how an enzyme changes shape during catalysis. Using an advanced technique called mix-and-inject serial crystallography at Japan's SACLA X-ray free-electron laser facility, the team observed domain movements and structural changes in the enzyme, copper amine oxidase enzyme over millisecond timescales, revealing dynamics that are nearly impossible to observe by other methods.

Researchers at the University of Tartu Institute of Computer Science, Junior Research Fellow of Artificial Intelligence Joonas Ariva and Associate Professor in Artificial Intelligence Dmytro Fishman, together with radiologists from Tartu University Hospital and engineers at Better Medicine, have developed an AI-based tool that accelerates the detection of kidney cancer. Its effectiveness was validated in a study published in Nature Communications Medicine.

A new 3D printing method developed by researchers at CUHK and USC eliminates the need for STL files in laser additive manufacturing.

By directly converting implicit geometries into optimized laser scanning toolpaths, the team achieved record-high printing resolution, faster computation, and stronger, smoother microscale metallic lattices.

This STL-free hybrid toolpath strategy reduces memory by 90%, shrinks wall thickness to 65 μm, and boosts strength by up to 66%. Applications range from aerospace brackets to copper heat exchangers.

An international research team led by Professor Philip C.Y. Chow at The University of Hong Kong (HKU) has unveiled a new catalyst that overcomes a major challenge in producing green hydrogen at scale. This innovation makes the process of producing oxygen efficiently and reliably in the harsh acidic environment used by today’s most promising industrial electrolysers.

A research team from the Faculty of Engineering at The University of Hong Kong (HKU) has harnessed citywide genetic data and developed a novel genome-resolved tracking method to uncover precisely how antibiotic-resistant bacteria and their resistance genes move across Hong Kong’s environment, offering vital insights into strategies for safeguarding public health.

35 million euros, 210 scientists, 12 years of research: after the maximum duration of three funding periods, the Transregional Collaborative Research Centre TRR 142 ‘Tailor-made non-linear photonics: From fundamental concepts to functional structures’ is officially winding down in December 2025. Scientists at Paderborn University and TU Dortmund University have achieved great things and literally shone a light into darkness with their research contributions.

Professor Nicholas X. Fang, Jockey Club STEM Professor in the Department of Mechanical Engineering, Faculty of Engineering, and Professor Xiang Zhang, HKU President and Vice-Chancellor, and Chair of Physics in the Department of Physics, Faculty of Science, have been jointly awarded the 2025 Brillouin Medal by the International Phononics Society (IPS). The honour recognises their pioneering discovery of ultrasonic metamaterials with negative elastic modulus.