The geometry of standard multi-well cell culture plates restricts oblique illumination angles, preventing matched illumination condition required for accurate tomographic reconstruction. To overcome this limitation, researchers developed the DF-FPDT technique, which leverages non-matched illumination and harnesses it as an intrinsic mechanism for dark-field-like contrast enhancement. By selectively updating high-frequency components using Phase Transfer Function (PTF) filtering, DF-FPDT effectively addresses low-frequency loss, enabling high-resolution, high-contrast live-cell imaging and dynamic screening, making DF-FPDT a powerful tool for biomedical research under realistic laboratory conditions.

One-third of epilepsy patients are resistant to medication. Deep brain stimulation of the centromedian nucleus (CM) is a promising treatment. However, accurately targeting the CM is challenging. This study explores new techniques like MP2RAGE imaging, diffusion tensor imaging, intraoperative microelectrode recordings, and connectivity mapping, which improve CM localization and electrode placement. This multimodal approach enhances electrode placement precision and seizure control, opening new treatment avenues for drug-resistant generalized and frontal lobe epilepsy.

The endowed chair was established through the support of TEAM GLOBAL, the technology holding founded by Berlin-based entrepreneur Lukasz Gadowski. With the appointment of Henry Sauermann, an internationally renowned scholar takes on a key role at the intersection of technology, innovation, and entrepreneurship.

Researchers from The Hong Kong University of Science and Technology and the Southern University of Science and Technology have developed a novel deep learning neural network, Electrode Net. By introducing signed distance fields and three-dimensional convolutional neural networks, this method can significantly accelerate electrode design while maintaining high accuracy. It is widely applicable to fuel cells, water electrolyzers, flow batteries, etc.

Stem cell transplantation can reverse stroke damage, researchers at the University of Zurich report. Its beneficial effects include regeneration of neurons and restoration of motor functions, marking a milestone in the treatment of brain disorders.

Wheat is one of the world's most important staple foods, especially in the form of bread. A joint study by the Leibniz Institute for Food Systems Biology at the Technical University of Munich (LSB) and the Leibniz Institute of Plant Genetics and Crop Plant Research (IPK) now shows that extremely dwarf wheat has a less favorable gluten composition than semi-dwarf, dwarf, or tall wild type wheat, and therefore produces flour with poorer baking properties.