Designing DNA nanostructures to create deformable and controllable biomolecular condensates
Peer-Reviewed Publication
Updates every hour. Last Updated: 20-Aug-2025 19:11 ET (20-Aug-2025 23:11 GMT/UTC)
Newly developed DNA nanostructures can form flexible, fluid, and stimuli-responsive condensates without relying on chemical cross-linking, report researchers from Institute of Science Tokyo and Chuo University. Owing to a rigid tetrahedral motif that binds the linkers in a specific direction, the resulting string-like structures form condensates with exceptional fluidity and stability. These findings pave the way for adaptive soft materials with potential applications in drug delivery, artificial organelles, and bioengineering platforms.
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