Tech & Engineering
Updates every hour. Last Updated: 3-Apr-2026 06:15 ET (3-Apr-2026 10:15 GMT/UTC)
The E3 ubiquitin ligase MIEL1 promotes thermo-responsive growth by blocking auto-ubiquitination and self-degradation of XBAT31
Science China PressPeer-Reviewed Publication
Global warming has severe impacts on plant growth and development, and XBAT31 controls the protein level of the thermosensor ELF3 to promote hypocotyl growth under warm temperature conditions. In the current study, researchers unveil MIEL1 as a stabilizer of XBAT31, suppressing its auto-ubiquitination independent of MIEL1’s canonical RING-domain activity, and act cooperatively to modulate hypocotyl elongation in response to warm temperature. This hierarchical interaction between two E3 ligases expands the paradigm of ubiquitin-mediated signaling in environmental adaptation.
- Journal
- Science Bulletin
Technion researchers develop AI model to predict chemotherapy benefit in breast cancer
Technion-Israel Institute of TechnologyPeer-Reviewed Publication
Researchers from the Technion – Israel Institute of Technology, in collaboration with international partners, have developed an artificial intelligence (AI) model that predicts both the risk of breast cancer recurrence and the likelihood of benefit from chemotherapy using standard pathology slides. The study, published in The Lancet Oncology and presented at ESMO, is the first to validate such a model using data from a large randomized clinical trial (TAILORx).
The AI system analyzes high-resolution digital images of tumor tissue and identifies complex visual patterns linked to cancer behavior and treatment response. It generates a score within minutes, offering a fast, low-cost, and widely accessible alternative to genomic tests such as Oncotype DX, which are expensive and not globally available.
The model was validated on thousands of patients across multiple countries and healthcare systems, demonstrating consistent performance. By enabling more accurate treatment decisions, the approach could reduce unnecessary chemotherapy and expand access to personalized cancer care, particularly in low-resource settings.
Researchers are now working toward clinical implementation and further development, including expansion to additional cancer types and treatments.
- Journal
- The Lancet Oncology
Scientists developed room-temperature, zero-power infrared sensor for next-generation night vision
Science China PressPeer-Reviewed Publication
Researchers have created a high-performance infrared detector that operates at room temperature without requiring external power or cooling. By growing high-quality lead sulfide films and using an asymmetric electrode design, the device achieves fast response and clear imaging, paving the way for affordable, compact infrared cameras in smartphones, automobiles, and security systems.
- Journal
- Science Bulletin
New lithium-ion battery design could power longer-lasting electric vehicles and portable devices
University of SurreyPeer-Reviewed Publication
- Journal
- ACS Applied Energy Materials
New satellite technology opens archaeological frontiers: Israel’s "Stonehenge" no longer stands alone
Ben-Gurion University of the NegevPeer-Reviewed Publication
- Journal
- PLOS One
Graz University of Technology researchers strengthen wood with needle and thread
Graz University of Technology- Funder
- Österreichische Forschungsförderungsgesellschaft
- Meeting
- 20th NAFEMS World Congress, NWC 2025