Loss of key visual channel triggers rhythmic retinal signals linked to night blindness
Peer-Reviewed Publication
Updates every hour. Last Updated: 3-Apr-2026 04:17 ET (3-Apr-2026 08:17 GMT/UTC)
Abnormal rhythmic electrical signals in the retina are a hallmark of several vision disorders, but their origins have remained unclear. Researchers have discovered how the loss of the TRPM1 ion channel disrupts communication between retinal cells, triggering oscillations that distort visual signaling. Oscillations observed in Trpm1 knockout mice are strikingly similar to those found in retinitis pigmentosa–model mice, revealing a common generative mechanism for these abnormal rhythmic signals in retinal diseases.
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