A study published in Cell advances understanding of how drugs shape vital cellular structures known as biomolecular condensates, blob-like mechanisms that drive gene regulation processes and have been linked to Alzheimer's, ALS and cancer.

A Virginia Tech-led team of international scientists has solved one of the last major mysteries in millipede evolution, revealing new clues about a group of animals that helped pave the way for life on land. The findings, published in Current Biology, complete the first evolutionary history of all living millipede orders. By combining genomic data from living species with morphological evidence from fossils, researchers traced the group's origins to nearly 460 million years ago — suggesting millipedes may have been present long before the oldest known millipede fossils.

Tumor cells coexist with diverse immune, stromal, and neural cells in a complex microenvironment. Recent single-cell and spatial transcriptomics have uncovered specialized cell subsets that drive cancer progression, immune evasion, and treatment response. A new review synthesizes these advances, introduces the “virtual tumor” concept for AI-driven ecosystem modeling, and outlines a roadmap from fundamental tumor microenvironment (TME) biology to next-generation precision immunotherapies targeting specific cell populations and their coordinated networks.