27-May-2026
Scientists mapped with unprecedented precision how genes shape our metabolism
Estonian Research CouncilPeer-Reviewed Publication
Led by University of Tartu researchers, the largest and most comprehensive study to date has been completed on how genetic differences between individuals influence metabolism.
- Journal
- Nature
- Funder
- The Estonian Genome Centre analyses were partially carried out in the High Performance Computing Center, University of Tartu. The research was conducted using the Estonian Center of Genomics/Roadmap II funded by the Estonian Research Council., We thank E. B. Fauman for feedback on an earlier version of the manuscript. This research has been conducted using the UK Biobank Resource under application, Nightingale Health Plc is acknowledged for early access to the UK Biobank NMR metabolite data., UCSF ChimeraX was developed by the Resource for Biocomputing, Visualization, and Informatics at the University of California, San Francisco, with support from National Institutes of Health R01-GM129325 and the Office of Cyber Infrastructure and Computational Biology, National Institute of Allergy and Infectious Diseases., K.A., R.T. and M.J. were supported by the Estonian Research Council, P.P., R.T., E.A, U.V., J.K. and T.E. were supported by the Estonian Research Council, I.R. was supported by the Estonian Research Council, U.V. was supported by the Estonian Research Council, E.A. was supported by University of Tartu Development Fund bridging, K.F. and A.K. were supported by the Estonian Research Council, Estonian Ministry of Education and Research Centres of Excellence, European Union’s Horizon Europe, N.T. was supported by the Estonian Research Council, Z.K. was supported by the Department of Computational Biology of the University of Lausanne