URochester researchers awarded up to $22M to study a hidden driver of aging
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Updates every hour. Last Updated: 13-Jun-2026 20:16 ET (14-Jun-2026 00:16 GMT/UTC)
What if people could stay healthier, stronger, and mentally sharper as they grow older—not by treating diseases one by one but by slowing a biological process that drives aging itself? A new University of Rochester–led research effort will test whether a drug originally developed to treat HIV can quiet a chronic immune response triggered by the body’s own DNA, to help preserve overall health and function later in life. The project is supported by a contract of up to $22 million over five years from the Advanced Research Projects Agency for Health (ARPA-H) and includes collaborators from Brown University, University of Connecticut, The University of Texas Medical Branch, University of Texas Health Houston, University of Nebraska, and Transposon Therapeutics.
Plastics shed thousands of chemicals into the sea, including oleamide – an industrial lubricant that also occurs naturally. In lab aquariums, researchers tracked 31,500 hunting interactions between the common octopus (Octopus vulgaris) and crabs, snails, and clams. Oleamide shifted octopus prey preference, dulled crustaceans’ predator avoidance, and increased encounters – without boosting successful kills. The subtle disruption lasted days, hinting that plastic chemicals could reshape coastal food webs by altering how species sense, feed, and interact. By mimicking biological signals, plastic-derived oleamide may quietly rewire marine behavior.
Artificial light at night (ALAN) can significantly affect animals by changing their physiology, behavior, and geographic distribution. However, how ALAN influences ecological and genetic patterns in closely related species remains unexplored. A new study investigated how ALAN shapes differences between two isopod species in Tokyo Bay, revealing clear ecological separation between the species based on patterns of nighttime urban lighting. The findings highlight how urban factors can be adjusted to support biodiversity.