A research team from the Institute of Aging and Regenerative Medicine at Jinan University, China, has examined how aging and disease are connected by exploring the aging-related remodeling of chromatin architecture. This study of chromatin architecture, the three-dimensional organization of DNA, gives scientists a better understanding of aging and its underlying mechanisms. Their review is published in Aging Research on May 8, 2026.

A new study investigates autologous rib cartilage resorption in microtia reconstruction, identifies fixation material-induced inflammation, gene dysregulation and mitochondrial dysfunction as key mechanisms, and provides insights for clinical intervention.

This review addresses the growing global burden of hereditary hearing loss, summarizes key advances in gene therapy, and aims to accelerate its clinical translation.

Type 2 diabetes (T2D) is marked by insulin resistance together with the progressive failure of pancreatic β-cells. Increasing evidence suggests that this failure is shaped not only by β-cells themselves, but also by the local islet immune microenvironment, where resident and recruited macrophages can influence inflammation, islet architecture, and insulin secretion. Exercise is a cornerstone of diabetes management, yet how it acts within this islet microenvironment has remained unclear.

A new fluorescent reporter capable of visualizing biologically active iron and oxygen inside living cells at single-cell resolution has been developed, as reported by researchers from Science Tokyo. Using this new tool, they revealed striking differences in the distribution of iron and oxygen across organs and even between neighboring cells of the same type. This innovation could serve as a platform for studying cancer, liver diseases, neurodegeneration, and aging.