The American Federation for Aging Research (AFAR) is pleased to announce the recipient of the 2025 Sagol Network GerOmic Award for Junior Faculty: Dheeraj Roy, PhD, Assistant Professor, University at Buffalo. Established in 2020, the Sagol Network GerOmic Award for Junior Faculty is a one- to two-year award given to junior faculty (MDs and PhDs) to conduct aging-related Omics (GerOmics) research.

Unless you’ve owned reptiles, you might not know that many of them “pee” crystals. Researchers publishing in the Journal of the American Chemical Society investigated the solid urine of more than 20 reptile species and found spheres of uric acid in all of them. This work reveals how reptiles uniquely package up and eliminate crystalline waste, which could inform future treatments for human conditions that also involve uric acid crystals: kidney stones and gout.

Carpenter ants are not squeamish when it comes to caring for the wounded. To minimise the risk of infection, the insects immediately amputate injured legs – thereby more than doubling their survival rate.

A study published in the International Journal of Oral Science reveals that the PLAGL1-IGF2 axis plays a vital role in postnatal jaw development. Using a mouse model, researchers showed that PLAGL1 regulates osteoblast differentiation in cranial neural crest cell-derived condyles. Deficiency in PLAGL1 disrupts bone formation, but treatment with IGF2 can rescue this effect. These findings provide new insights into craniofacial development and potential therapeutic targets for mandibular disorders.