A new study published in Molecular Psychiatry reveals that the biological underpinnings of autism and ADHD may transcend traditional diagnostic boundaries. Researchers from the Child Mind Institute and collaborating institutions discovered that autism symptom severity, rather than diagnostic classification, corresponds to distinct patterns of brain connectivity and related gene expression in children diagnosed with either autism spectrum disorder (ASD) or attention-deficit/hyperactivity disorder (ADHD). This finding supports an evolving clinical and research landscape that aims to better define the roots of neurodevelopmental co-occurrences.

Researchers at HHMI's Janelia Research Campus have uncovered a novel way that two of the structures inside cells—the endoplasmic reticulum (ER) and lysosomes—coordinate the production of proteins, highlighting how interactions between organelles are important for regulating cellular processes. 

Scientists compared what California sea lions eat in the Channel Islands (U.S.) and the Gulf of California (Mexico), they expected to find a clear explanation for why populations were booming in California but shrinking in Mexico. Instead, they found something more complicated.

Alzheimer’s Disease (AD), the leading cause of dementia, affects nearly 40 million individuals globally, resulting in a gradual loss of memory and independence. Despite extensive research over the past decades, no treatments have been found that can halt or reverse the progression of this devastating disease. A groundbreaking international study shows how boosting a natural molecule can help restore memory in animal models of Alzheimer’s disease. The new study offers hope for developing new therapies for patients with Alzheimer’s disease.

A new technique should help answer questions about how phages work and may lead the way to new, specialized therapies.