Skin can ‘pre-learn’: Priming cells for regeneration before injury
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Updates every hour. Last Updated: 3-Jun-2026 18:17 ET (3-Jun-2026 22:17 GMT/UTC)
POSTECH reveals how mosaic partial reprogramming enhances wound repair responses.
Salk Institute scientist Sreekanth Chalasani, PhD, has received an award of up to $41.3 million from the Advanced Research Projects Agency for Health (ARPA-H) to transform his lab’s sonogenetics discovery—using ultrasound to precisely control mammalian cells—into a potential new therapy for a number of human conditions, such as peripheral neuropathies.
Researchers have discovered a new species of glassfrog in Ecuador – the Dajomes glassfrog – named after Neisi Dajomes, the first Ecuadorian woman to receive an Olympic gold medal, which she won in Tokyo 2020 in women's 76 kg weightlifting. Mylena Masache, a Biology student of the Pontificia Universidad Católica del Ecuador, and colleagues, describe the frog in a new study published April 8, 2026 in the open-access journal PLOS One.
In recent decades, the zebrafish has become one of the most valuable model organisms in scientific research. For a variety of reasons, including their genetic similarities to humans, these tiny tropical fish have helped researchers unlock secrets to diseases ranging from muscular dystrophy to melanoma.
Now, Yale researchers are hoping the zebrafish will do the same for autism spectrum disorder.
In a new study, a research team generated a database of 520 U.S. Food and Drug Administration (FDA)-approved drugs and their effects on basic larval zebrafish behaviors and then used the database to identify drug candidates that reverse disrupted behaviors in zebrafish carrying mutations in autism risk genes.
These drug candidates, the researchers say, might represent targets for people carrying mutations in specific autism risk genes.
“Because autism spectrum disorder is highly clinically and genetically heterogeneous, it is challenging to identify drug candidates and many new drugs under investigation are not effective in clinical trials,” said Ellen J. Hoffman, an associate professor at the Yale Child Study Center at Yale School of Medicine (YSM) and senior author of the new study.
“Our study highlights the importance of stratifying or subgrouping autism risk genes to identify potential drug candidates using a precision medicine-based approach.”
The study appears in the journal Proceedings of the National Academy of Sciences.
Scripps Research chemists solve a longstanding problem in the construction of branched molecular frameworks, unlocking a faster path to the complex structures found in drugs and materials.
In a new study published in Nature, researchers describe the extraordinary preservation of the oldest known costal breathing system in a mummified fossil from the early Permian period. The mummified fossil, which is only a few inches long, preserves not only bones, but also three-dimensional skin, calcified cartilage, and — most astonishingly —protein remnants that predate the previous oldest-known example by nearly 100 million years.