UOsaka and MIT scientists revealed that the motor proteins KIF18A and CENP-E work together to align chromosomes during mitosis. Cancer cells with reduced CENP-E levels are especially sensitive to KIF18A inhibition, and dual inhibition of both proteins leads to efficient cell death. The discovery offers new insights into chromosome mechanics and a potential strategy for targeted cancer therapy.

Exercise-induced angiogenesis and lymphangiogenesis offer promising anti-aging benefits by improving vascular and immune system function. A review from researchers in China found that exercise activates key molecular pathways boosting blood and lymphatic vessel growth, which enhances tissue repair and metabolic regulation. This approach may serve as a therapeutic strategy to counteract age-related decline and diseases, with potential for personalized exercise interventions improving health and longevity.