Medication-induced sterol disruption: A silent threat to brain development and public health
Reports and Proceedings
Updates every hour. Last Updated: 25-Apr-2025 02:08 ET (25-Apr-2025 06:08 GMT/UTC)
An editorial published in Brain Medicine reveals that many widely prescribed medications may disrupt sterol biosynthesis—an essential process for brain development—potentially causing harm similar to devastating genetic disorders. This urgent call to action highlights how current drug approval processes fail to account for drug interactions that could harm developing brains.
BALTIMORE, MD, April 21, 2025 – Courts around the world are struggling to keep up with growing caseloads, leaving individuals and businesses waiting months – sometimes years – for resolution. But a new study in the INFORMS journal Manufacturing & Service Operations Management has uncovered a surprisingly simple way to speed up the system that doesn’t require hiring more judges.
A new study published in JAMA Internal Medicine found that hospitalized patients with alcohol use disorder who began taking the AUD medication naltrexone before they were discharged were able to reduce heavy drinking in the three-month period following their hospital stay. The findings specifically showed that both forms of naltrexone, which is offered as a pill or as an extended-release injectable, were similarly effective at reducing patients’ alcohol consumption. After three months of treatment, heavy drinking within the last 30 days decreased by approximately 38 percentage points among patients who took the oral version of naltrexone, compared to about a 46 percentage-point decrease among patients who received the injectable version of the medication.