A comprehensive peer-reviewed viewpoint published in Psychedelics examines how psychedelic substances could transform treatment approaches for stress-related psychiatric disorders. Xiaohui Wang from Changchun Institute of Applied Chemistry, Chinese Academy of Sciences,  analyze neurobiological mechanisms including serotonin 2A receptor activation, neuroplasticity enhancement, and inflammation reduction. The authors propose psychedelics address root causes rather than symptoms alone, offering hope for treatment-resistant conditions.

The University of Osaka scientists have developed a safe, efficient “dump-and-stir” method to introduce ortho-carborane into various aromatic compounds using a newly designed lithium–copper reagent. This innovation overcomes the complexity and hazards of previous methods, paving the way for new applications in boron neutron capture therapy (BNCT), three-dimensional aromatic materials, and bioisosteric drug design.