In a paper published in Science Bulletin, the research teams led by Professor Shunmin He, Professor Runsheng Chen, and Professor Tao Xu from the Institute of Biophysics, Chinese Academy of Sciences, introduced TOAnnoPriDB—a comprehensive resource for annotating and prioritizing non-coding variants across the human genome. This represents the seventh publication from the NyuWa genome project. TOAnnoPriDB integrates trans-omic data from 147 public resources, including six databases previously developed by the team: NyuWa, NONCODE, NPInter, piRBase, SmProt, and LncVar. It features a framework for assessing the functional impact of variants and offers a user-friendly web interface. The database empowers researchers to prioritize and analyze variants, advancing studies on variant functions and disease-related research in humans.

Green hydrogen from water splitting has emerged as a critical energy vector with the potential to spearhead the global transition to a fossil fuel-independent society. The feld of catalysis has been revolutionized by single-atom catalysts (SACs), which exhibit unique and intricate interactions between atomically dispersed metal atoms and their supports. Recently, bimetallic SACs (bimSACs) have garnered signifcant attention for leveraging the synergistic functions of two metal ions coordinated on appropriately designed supports. BimSACs ofer an avenue for rich metal–metal and metal–support cooperativity, potentially addressing current limitations of SACs in efectively furnishing transformations which involve synchronous proton–electron exchanges, substrate activation with reversible redox cycles, simultaneous multi-electron transfer, regulation of spin states, tuning of electronic properties, and cyclic transition states with low activation energies. This review aims to encapsulate the growing advancements in bimSACs, with an emphasis on their pivotal role in hydrogen generation via water splitting. We subsequently delve into advanced experimental methodologies for the elaborate characterization of SACs, elucidate their electronic properties, and discuss their local coordination environment. Overall, we present comprehensive discussion on the deployment of bimSACs in both hydrogen evolution reaction and oxygen evolution reaction, the two half-reactions of the water electrolysis process.

Here, researchers from Nanjing University of Aeronautics and Astronautics propose to control thermal stress at coating interfaces during laser induction processes and demonstrate a novel process for precisely graphenizing ultra-thin diamond coating surface through laser induction and mechanical cleavage, without damaging the substrates.

Their work provides an effective and cost-efficient avenue to overcome application bottlenecks in engineered diamond surfaces, expanding their use in friction pairs such as cutting tools, bearings, and mechanical seals. Moreover, it may facilitate advancements in multicarbon heterostructures and their preparation methods, supporting potential applications in electronics, aviation, and biomedicine involving diamond, graphene, and all-carbon devices.