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Updates every hour. Last Updated: 26-Jan-2026 20:11 ET (27-Jan-2026 01:11 GMT/UTC)

26-Jan-2026

Brewing possibilities: Using caffeine to edit gene expression

What if a cup of coffee could help treat cancer? Researchers at the Texas A&M Health Institute of Biosciences and Technology believe it’s possible. By combining caffeine with the use of CRISPR — a gene-editing tool known as clustered regularly interspaced short palindromic repeats — scientists are unlocking new treatments for long term diseases, like cancer and diabetes, using a strategy known as chemogenetics.

Journal: Chemical Science
Funder: NIH/National Institutes of Health, Welch Foundation, Leukemia and Lymphoma Society, Cancer Prevention and Research Institute of Texas

26-Jan-2026

Tumor-associated macrophages (TAMs): Constructing an immunosuppressive microenvironment bridge for pancreatic ductal adenocarcinoma (PDAC)

Chinese Medical Journals Publishing House Co., Ltd.

Highlights

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Tumor-associated macrophages (TAMs) have the ability to promote and inhibit pancreatic ductal adenocarcinoma (PDAC).

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Crosstalk between TAMs and immune cells is the key to an immunosuppressive microenvironment.

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Targeting TAMs for reverse immunosuppression is a future direction of PDAC treatment.

Journal: Cancer Pathogenesis and Therapy

26-Jan-2026

Role of Candida albicans in chronic inflammation and the development of oral squamous cell carcinoma

Chinese Medical Journals Publishing House Co., Ltd.

Highlights

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Persistent Candida albicans infections are strongly correlated with oral carcinogenesis.
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Candida-induced inflammation promotes oxidative stress, cytokine imbalances, and genomic instability.
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Biofilm formation, epithelial invasion, and immune evasion contribute to oral carcinogenesis.
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Early detection and management of Candida infections and good oral hygiene are crucial for reducing the risk of oral cancer.

Journal: Cancer Pathogenesis and Therapy

25-Jan-2026

Relationship between visceral obesity and prognosis in patients with stage IVB cervical cancer receiving radiotherapy and chemotherapy

Chinese Medical Journals Publishing House Co., Ltd.

Highlights

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In patients with stage IVB cervical cancer, the overall survival (OS) rate of patients with high visceral-to-subcutaneous adipose tissue area ratio (VSR) is significantly higher than those with low VSR.

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A low VSR is an independent risk factor for poor prognosis in patients with stage IVB cervical cancer.

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Visceral obesity before chemoradiotherapy has a protective effect on the prognosis of patients with stage IVB cervical cancer.

Journal: Cancer Pathogenesis and Therapy

25-Jan-2026

Materials chemistry: Uncovering the low-temperature oxygen storage and release mechanism of Mn–CeO2 nanoparticles

Advanced Institute for Materials Research (AIMR), Tohoku University

Precise control of local structure has long limited efforts to understand how dopants enhance lattice oxygen storage and release of ceria-based materials. Using a continuous-flow hydrothermal method, AIMR researchers synthesized ultrasmall Mn–CeO2 nanoparticles with tunable Mn environments, revealing distinct low- and high-temperature mechanisms and achieving a fourfold boost in low-temperature oxygen storage and release capacity.

Journal: Chemistry of Materials

24-Jan-2026

Mapping genetic variations: Insights into pear domestication and breeding

Nanjing Agricultural University The Academy of Science

This research provides a comprehensive analysis of deleterious mutations in pear (Pyrus spp.) during domestication, shedding light on their impact on agronomic traits.

Journal: Horticulture Research

24-Jan-2026

Safety Emergency Science (SES) releases first issue (2025, Volume 1, Issue 1)

Tsinghua University Press

Safety Emergency Science (SES), China’s first international academic journal dedicated to safety and emergency science and technology, has officially launched its debut issue (Volume 1, Issue 1) in March 2025.

24-Jan-2026

Safety Emergency Science (SES) Releases Issue 2 (2025, Volume 1)

Tsinghua University Press

Safety Emergency Science (SES), China’s first international academic journal dedicated to safety and emergency science and technology, has officially launched its debut issue (Volume 1, Issue 2).

24-Jan-2026

Genetic insights for prunus: mapping key traits for future breeding

Nanjing Agricultural University The Academy of Science

This research explores 25 years of curated genetic data to identify critical genomic regions linked to key traits in Prunus crops such as peaches, almonds, apricots, and sweet cherries.

Journal: Horticulture Research

23-Jan-2026

AI tool differentiates between tumors in shared brain region

Thomas Jefferson University

Automated machine learning can accurately identify two types of benign tumors that develop in the same space within the brain