Researchers at the National University of Singapore (NUS) have developed a scalable, non-viral technology that efficiently delivers genetic material into human immune cells. The platform, called Nanostraw Electro-actuated Transfection (NExT), uses tiny hollow nanostructures and electrical pulses to insert a wide variety of biomolecules — proteins, mRNA and gene-editing tools — into immune cells with high efficiency and minimal disruption.

The Korea Institute of Machinery and Materials (President Seog-Hyeon Ryu, hereinafter referred to as KIMM), under the National Research Council of Science & Technology (Chairperson Kim, Yeung-Shik), has developed a technology that stably generates high photocurrent under natural sunlight to efficiently produce hydrogen.

In the latest issue of the International Journal of Extreme Manufacturing, Professor Jiankang He and his team from Xi'an Jiaotong University introduce new frontiers for the regeneration and functionality enhancement of excitable tissues by integrating bioelectronics with bioengineered constructs.

Their work not only deepens our understanding of the role of electrical microenvironments in tissue development but also sets forth critical design principles for creating bioelectronic-tissue construct hybrids. These advancements hold transformative potential for repairing and restoring damaged excitable tissues such as cardiac, neural, and muscle tissues.

Research team published a comprehensive review on circRNA-disease association prediction, summarizing computational models into four categories and analyzing their strengths and limitations. Challenges like data imbalance and insufficient fusion of biological information are highlighted.